Human Immunodeficiency Virus Type 1 Coreceptor Preferences Determine Target T-Cell Depletion and Cellular Tropism in Human Lymphoid Tissue

The present study sought to determine how usage of coreceptors by human immunodeficiency virus type 1 dictates cell tropism and depletion of CD4(+) T cells in human lymphoid tissues cultured ex vivo. We found that coreceptor preferences control the marked, preferential depletion of coreceptor-expres...

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Bibliographische Detailangaben
Hauptverfasser: Grivel, Jean-Charles, Penn, Michael L., Eckstein, Daniel A., Schramm, Birgit, Speck, Roberto F., Abbey, Nancy W., Herndier, Brian, Margolis, Leonid, Goldsmith, Mark A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC110890/
https://ncbi.nlm.nih.gov/pubmed/10799612
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