Human Immunodeficiency Virus Type 1 (HIV-1) Non-B Subtypes Are Similar to HIV-1 Subtype B in that Coreceptor Specificity Is a Determinant of Cytopathicity in Human Lymphoid Tissue Infected Ex Vivo

We sought to determine the relationship between virus-mediated CD4(+) T-lymphocyte cytopathicity and viral coreceptor preference among various human immunodeficiency virus type 1 (HIV-1) subtypes in an ex vivo-infected human lymphoid tissue model. Our data show that all R5 HIV-1 infections resulted...

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Библиографические подробности
Главные авторы: Malkevich, Nina, Womack, Chad, Pandya, Punita, Grivel, Jean-Charles, Fauci, Anthony S., Margolis, Leonid
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2001
Предметы:
Virus-Cell Interactions
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC114630/
https://ncbi.nlm.nih.gov/pubmed/11581424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.21.10520-10522.2001
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