Fourteen Residues of the U1 snRNP-Specific U1A Protein Are Required for Homodimerization, Cooperative RNA Binding, and Inhibition of Polyadenylation

It was previously shown that the human U1A protein, one of three U1 small nuclear ribonucleoprotein-specific proteins, autoregulates its own production by binding to and inhibiting the polyadenylation of its own pre-mRNA. The U1A autoregulatory complex requires two molecules of U1A protein to cooper...

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Bibliografske podrobnosti

izdano v:	Mol Cell Biol
Principais autores:	Klein Gunnewiek, Jacqueline M. T., Hussein, Reem I., van Aarssen, Yvonne, Palacios, Daphne, de Jong, Rob, van Venrooij, Walther J., Gunderson, Samuel I.
Format:	Artigo
Jezik:	Inglês
Izdano:	Taylor & Francis 2000
Teme:	Gene Expression
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110837/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10688667/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.6.2209-2217.2000
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