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Apoptotic and Growth-Promoting Activity of E2F Modulated by MDM2

E2F integrates and coordinates cell cycle progression with the transcription apparatus through its cyclical interactions with important regulators of cellular proliferation, such as pRb, cyclins, and cdk's. Physiological E2F is a heterodimeric transcription factor composed of an E2F and a DP fa...

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Hlavní autoři: Loughran, Öonagh, La Thangue, Nicholas B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC110835/
https://ncbi.nlm.nih.gov/pubmed/10688665
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