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Activation of the BRLF1 promoter and lytic cycle of Epstein–Barr virus by histone acetylation
Histone acetylation alters the chromatin structure and activates the genes that are repressed by histone deacetylation. This investigation demonstrates that treating P3HR1 cells with trichostatin A (TSA) activates the Epstein–Barr virus (EBV) lytic cycle, allowing the virus to synthesize three viral...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC110796/ https://ncbi.nlm.nih.gov/pubmed/11024171 |
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