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Activation of the BRLF1 promoter and lytic cycle of Epstein–Barr virus by histone acetylation

Histone acetylation alters the chromatin structure and activates the genes that are repressed by histone deacetylation. This investigation demonstrates that treating P3HR1 cells with trichostatin A (TSA) activates the Epstein–Barr virus (EBV) lytic cycle, allowing the virus to synthesize three viral...

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Hlavní autoři: Chang, Li-Kwan, Liu, Shih-Tung
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC110796/
https://ncbi.nlm.nih.gov/pubmed/11024171
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