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Base excision repair is efficient in cells lacking poly(ADP-ribose) polymerase 1

Poly(ADP-ribose) polymerase 1 (PARP-1) is a nuclear enzyme that is activated by binding to DNA breaks induced by ionizing radiation or through repair of altered bases in DNA by base excision repair. Mice lacking PARP-1 and, in certain cases, the cells derived from these mice exhibit hypersensitivity...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vodenicharov, Momchil D., Sallmann, Frédéric R., Satoh, Masahiko S., Poirier, Guy G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC110786/
https://ncbi.nlm.nih.gov/pubmed/11024167
Tagiau: Ychwanegu Tag
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