DNA-binding mechanism of the Escherichia coli Ada O(6)-alkylguanine–DNA alkyltransferase
The C-terminal domain of the Escherichia coli Ada protein (Ada-C) aids in the maintenance of genomic integrity by efficiently repairing pre-mutagenic O(6)-alkylguanine lesions in DNA. Structural and thermodynamic studies were carried out to obtain a model of the DNA-binding process. Nuclear magnetic...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2000
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110768/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11000262/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.19.3710 |
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