Functional significance of conserved residues in the phosphohydrolase module of Escherichia coli MutT protein
Escherichia coli MutT protein hydrolyzes 8-oxo-7,8-dihydro-2′-dGTP (8-oxo-dGTP) to the monophosphate, thus avoiding the incorporation of 8-oxo-7,8-dihydroguanine (8-oxo-G) into nascent DNA. Bacterial and mammalian homologs of MutT protein share the phosphohydrolase module (MutT: Gly37→Gly59). By sat...
में बचाया:
| में प्रकाशित: | Nucleic Acids Res |
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| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2000
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10954591/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.17.3240 |
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