Functional significance of conserved residues in the phosphohydrolase module of Escherichia coli MutT protein
Escherichia coli MutT protein hydrolyzes 8-oxo-7,8-dihydro-2′-dGTP (8-oxo-dGTP) to the monophosphate, thus avoiding the incorporation of 8-oxo-7,8-dihydroguanine (8-oxo-G) into nascent DNA. Bacterial and mammalian homologs of MutT protein share the phosphohydrolase module (MutT: Gly37→Gly59). By sat...
I tiakina i:
| I whakaputaina i: | Nucleic Acids Res |
|---|---|
| Ngā kaituhi matua: | , , , , |
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
Oxford University Press
2000
|
| Ngā marau: | |
| Urunga tuihono: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10954591/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.17.3240 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
|
