Functional significance of conserved residues in the phosphohydrolase module of Escherichia coli MutT protein

Escherichia coli MutT protein hydrolyzes 8-oxo-7,8-dihydro-2′-dGTP (8-oxo-dGTP) to the monophosphate, thus avoiding the incorporation of 8-oxo-7,8-dihydroguanine (8-oxo-G) into nascent DNA. Bacterial and mammalian homologs of MutT protein share the phosphohydrolase module (MutT: Gly37→Gly59). By sat...

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Xehetasun bibliografikoak
Egile Nagusiak: Shimokawa, Hidetoshi, Fujii, Yoshimitsu, Furuichi, Masato, Sekiguchi, Mutsuo, Nakabeppu, Yusaku
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2000
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC110708/
https://ncbi.nlm.nih.gov/pubmed/10954591
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