Functional significance of conserved residues in the phosphohydrolase module of Escherichia coli MutT protein

Escherichia coli MutT protein hydrolyzes 8-oxo-7,8-dihydro-2′-dGTP (8-oxo-dGTP) to the monophosphate, thus avoiding the incorporation of 8-oxo-7,8-dihydroguanine (8-oxo-G) into nascent DNA. Bacterial and mammalian homologs of MutT protein share the phosphohydrolase module (MutT: Gly37→Gly59). By sat...

Olles dieđut

Bibliográfalaš dieđut

Publikašuvnnas:	Nucleic Acids Res
Váldodahkkit:	Shimokawa, Hidetoshi, Fujii, Yoshimitsu, Furuichi, Masato, Sekiguchi, Mutsuo, Nakabeppu, Yusaku
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Oxford University Press 2000
Fáttát:	Article
Liŋkkat:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10954591/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.17.3240
Fáddágilkorat:	Lasit fáddágilkoriid Eai fáddágilkorat, Lasit vuosttaš fáddágilkora!