p300 Mediates Transcriptional Stimulation by the Basic Helix-Loop-Helix Activators of the Insulin Gene

Pancreatic β-cell-type-specific and glucose-inducible transcription of the insulin gene is mediated by the basic helix-loop-helix factors that bind to and activate expression from an E-box element within its enhancer. The E-box activator is a heteromeric complex composed of a β-cell-enriched factor,...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Qiu, Yi, Sharma, Arun, Stein, Roland
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1998
Schlagworte:	Transcriptional Regulation
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110675/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9566915/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.5.2957
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