Molecular Evolution Allows Bypass of the Requirement for Activation Loop Phosphorylation of the Cdc28 Cyclin-Dependent Kinase
Many protein kinases are regulated by phosphorylation in the activation loop, which is required for enzymatic activity. Glutamic acid can substitute for phosphothreonine in some proteins activated by phosphorylation, but this substitution (T169E) at the site of activation loop phosphorylation in the...
Bewaard in:
| Gepubliceerd in: | Mol Cell Biol |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Taylor & Francis
1998
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110671/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9566911/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.5.2923 |
| Tags: |
Geen labels, Wees de eerste die dit record labelt!
|