Genetic Evidence of a Role for Lck in T-Cell Receptor Function Independent or Downstream of ZAP-70/Syk Protein Tyrosine Kinases

T-cell antigen receptor (TCR) engagement results in sequential activation of the Src protein tyrosine kinases (PTKs) Lck and Fyn and the Syk PTKs, ZAP-70 and Syk. While the Src PTKs mediate the phosphorylation of TCR-associated signaling subunits and the phosphorylation and activation of the Syk PTK...

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Bibliografske podrobnosti

izdano v:	Mol Cell Biol
Principais autores:	Wong, Jane, Straus, David, Chan, Andrew C.
Format:	Artigo
Jezik:	Inglês
Izdano:	Taylor & Francis 1998
Teme:	Cell Growth and Development
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110664/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9566904/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.5.2855
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