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Tumor Suppressor p53 Can Participate in Transcriptional Induction of the GADD45 Promoter in the Absence of Direct DNA Binding

The GADD45 gene is a growth arrest-associated gene that is induced by certain DNA-damaging agents and other stresses, such as starvation, in all mammalian cells. In addition to a strong p53-binding element in an intronic sequence, we have recently found that p53, while not required or sufficient alo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhan, Qimin, Chen, I-Tsuen, Antinore, Michael J., Fornace, Albert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC110656/
https://ncbi.nlm.nih.gov/pubmed/9566896
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