Double-Stranded RNA-Independent Dimerization of Interferon-Induced Protein Kinase PKR and Inhibition of Dimerization by the Cellular P58(IPK) Inhibitor

The interferon (IFN)-induced, double-stranded RNA-activated protein kinase (PKR) mediates the antiviral and antiproliferative actions of IFN, in part, via its translational inhibitory properties. Previous studies have demonstrated that PKR forms dimers and that dimerization is likely to be required...

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Hlavní autoři: Tan, Seng-Lai, Gale, Michael J., Katze, Michael G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1998
Témata:
Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC110623/
https://ncbi.nlm.nih.gov/pubmed/9566864
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