Double-Stranded RNA-Independent Dimerization of Interferon-Induced Protein Kinase PKR and Inhibition of Dimerization by the Cellular P58(IPK) Inhibitor

The interferon (IFN)-induced, double-stranded RNA-activated protein kinase (PKR) mediates the antiviral and antiproliferative actions of IFN, in part, via its translational inhibitory properties. Previous studies have demonstrated that PKR forms dimers and that dimerization is likely to be required...

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Detalles Bibliográficos
Main Authors: Tan, Seng-Lai, Gale, Michael J., Katze, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1998
Assuntos:
Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC110623/
https://ncbi.nlm.nih.gov/pubmed/9566864
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