The African Swine Fever Virus Thymidine Kinase Gene Is Required for Efficient Replication in Swine Macrophages and for Virulence in Swine

African swine fever virus (ASFV) replicates in the cytoplasm of infected cells and contains genes encoding a number of enzymes needed for DNA synthesis, including a thymidine kinase (TK) gene. Recombinant TK gene deletion viruses were produced by using two highly pathogenic isolates of ASFV through...

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書誌詳細

出版年:	J Virol
主要な著者:	Moore, D. M., Zsak, L., Neilan, J. G., Lu, Z., Rock, D. L.
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 1998
主題:	Viral Pathogenesis and Immunity
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110620/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811782/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.12.10310-10315.1998
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