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Mechanism of Interferon Action: Identification of Essential Positions within the Novel 15-Base-Pair KCS Element Required for Transcriptional Activation of the RNA-Dependent Protein Kinase pkr Gene

RNA-dependent protein kinase PKR is an important regulator of gene expression in interferon (IFN)-treated and virus-infected cells. The 50-kb gene encoding human PKR kinase (pkr) is inducible by IFN. Transfection analyses, using chloramphenicol acetyltransferase (CAT) as the reporter in constructs p...

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Bibliografski detalji
Glavni autori: Kuhen, Kelli L., Vessey, Jill W., Samuel, Charles E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC110506/
https://ncbi.nlm.nih.gov/pubmed/9811730
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