Self-Inactivating Lentivirus Vector for Safe and Efficient In Vivo Gene Delivery

In vivo transduction of nondividing cells by human immunodeficiency virus type 1 (HIV-1)-based vectors results in transgene expression that is stable over several months. However, the use of HIV-1 vectors raises concerns about their safety. Here we describe a self-inactivating HIV-1 vector with a 40...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Zufferey, Romain, Dull, Thomas, Mandel, Ronald J., Bukovsky, Anatoly, Quiroz, Dulce, Naldini, Luigi, Trono, Didier
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Gene Therapy
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110499/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811723/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.12.9873-9880.1998
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