Self-Inactivating Lentivirus Vector for Safe and Efficient In Vivo Gene Delivery

In vivo transduction of nondividing cells by human immunodeficiency virus type 1 (HIV-1)-based vectors results in transgene expression that is stable over several months. However, the use of HIV-1 vectors raises concerns about their safety. Here we describe a self-inactivating HIV-1 vector with a 40...

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Bibliografske podrobnosti
Main Authors: Zufferey, Romain, Dull, Thomas, Mandel, Ronald J., Bukovsky, Anatoly, Quiroz, Dulce, Naldini, Luigi, Trono, Didier
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Gene Therapy
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC110499/
https://ncbi.nlm.nih.gov/pubmed/9811723
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