Study of Dengue Virus Infection in SCID Mice Engrafted with Human K562 Cells

Here we report that severe combined immunodeficient (SCID) mice engrafted with human K562 cells (K562-SCID mice) can be used as an animal model to study dengue virus (DEN) infection. After intratumor injection into K562 cell masses of PL046, a Taiwanese DEN-2 human isolate, the K562-SCID mice showed...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Lin, Yi-Ling, Liao, Ching-Len, Chen, Li-Kuang, Yeh, Chia-Tsui, Liu, Chiu-I, Ma, Shiou-Hwa, Huang, Yu-Ying, Huang, Yue-Ling, Kao, Chuan-Liang, King, Chwan-Chuen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Viral Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110483/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811707/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.12.9729-9737.1998
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