Study of Dengue Virus Infection in SCID Mice Engrafted with Human K562 Cells

Here we report that severe combined immunodeficient (SCID) mice engrafted with human K562 cells (K562-SCID mice) can be used as an animal model to study dengue virus (DEN) infection. After intratumor injection into K562 cell masses of PL046, a Taiwanese DEN-2 human isolate, the K562-SCID mice showed...

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Bibliografiska uppgifter
Huvudupphovsmän: Lin, Yi-Ling, Liao, Ching-Len, Chen, Li-Kuang, Yeh, Chia-Tsui, Liu, Chiu-I, Ma, Shiou-Hwa, Huang, Yu-Ying, Huang, Yue-Ling, Kao, Chuan-Liang, King, Chwan-Chuen
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1998
Ämnen:
Viral Pathogenesis and Immunity
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC110483/
https://ncbi.nlm.nih.gov/pubmed/9811707
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