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Recombinant Herpes Simplex Virus Type 1 Engineered for Targeted Binding to Erythropoietin Receptor-Bearing Cells

The utility of recombinant herpes simplex virus type 1 (HSV-1) vectors may be expanded by manipulation of the virus envelope to achieve cell-specific gene delivery. To this end, an HSV-1 mutant virus deleted for glycoprotein C (gC) and the heparan sulfate binding domain of gB (KgBpK(−)gC(−)) was eng...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Laquerre, Sylvie, Anderson, Dina B., Stolz, Donna B., Glorioso, Joseph C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110478/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811702/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.12.9683-9697.1998
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