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Recombinant Herpes Simplex Virus Type 1 Engineered for Targeted Binding to Erythropoietin Receptor-Bearing Cells

The utility of recombinant herpes simplex virus type 1 (HSV-1) vectors may be expanded by manipulation of the virus envelope to achieve cell-specific gene delivery. To this end, an HSV-1 mutant virus deleted for glycoprotein C (gC) and the heparan sulfate binding domain of gB (KgBpK(−)gC(−)) was eng...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Laquerre, Sylvie, Anderson, Dina B., Stolz, Donna B., Glorioso, Joseph C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC110478/
https://ncbi.nlm.nih.gov/pubmed/9811702
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