Up to 100-Fold Increase of Apparent Gene Expression in the Presence of Epstein-Barr Virus oriP Sequences and EBNA1: Implications of the Nuclear Import of Plasmids

A 100-fold increase in luciferase activity was observed in 293 cells, stably expressing Epstein-Barr nuclear antigen 1 (EBNA1; 293-EBNA1 cells), that had been transiently transfected with plasmids carrying Epstein-Barr virus (EBV) oriP sequences. This increase was observed in comparison to reporter...

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Bibliografiska uppgifter
Huvudupphovsmän: Längle-Rouault, Françoise, Patzel, Volker, Benavente, Annie, Taillez, Martine, Silvestre, Nathalie, Bompard, Albine, Sczakiel, Georg, Jacobs, Eric, Rittner, Karola
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1998
Ämnen:
Gene Therapy
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC110430/
https://ncbi.nlm.nih.gov/pubmed/9621086
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