Role of E4 in Eliciting CD4 T-Cell and B-Cell Responses to Adenovirus Vectors Delivered to Murine and Nonhuman Primate Lungs

Adenovirus vectors delivered to lung are being considered in the treatment of cystic fibrosis (CF). Vectors from which E1 has been deleted elicit T- and B-cell responses which confound their use in the treatment of chronic diseases such as CF. In this study, we directly compare the biology of an ade...

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Publié dans:	J Virol
Auteurs principaux:	Chirmule, Narendra, Hughes, Joseph V., Gao, Guang-Ping, Raper, Steven E., Wilson, James M.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1998
Sujets:	Gene Therapy
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110420/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9621078/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.7.6138-6145.1998
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