Role of the SH3-Ligand Domain of Simian Immunodeficiency Virus Nef in Interaction with Nef-Associated Kinase and Simian AIDS in Rhesus Macaques

The nef gene of the human and simian immunodeficiency viruses (HIV and SIV) is dispensable for viral replication in T-cell lines; however, it is essential for high virus loads and progression to simian AIDS (SAIDS) in SIV-infected adult rhesus macaques. Nef proteins from HIV type 1 (HIV-1), HIV-2, a...

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Bibliographic Details
Main Authors: Khan, Imran H., Sawai, Earl T., Antonio, Erwin, Weber, Claudia J., Mandell, Carol P., Montbriand, Phillip, Luciw, Paul A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Viral Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC110384/
https://ncbi.nlm.nih.gov/pubmed/9621042
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