A Small Yeast RNA Blocks Hepatitis C Virus Internal Ribosome Entry Site (HCV IRES)-Mediated Translation and Inhibits Replication of a Chimeric Poliovirus under Translational Control of the HCV IRES Element

Eitemau Tebyg

• A Small Yeast RNA Blocks Hepatitis C Virus Internal Ribosome Entry Site (HCV IRES)-Mediated Translation and Inhibits Replication of a Chimeric Poliovirus under Translational Control of the HCV IRES Element
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• IRES-induced conformational changes in the ribosome and the mechanism of translation initiation by internal ribosomal entry
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• Irresistible IRES: Attracting the translation machinery to internal ribosome entry sites
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  Cyhoeddwyd: (2001)
• HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation
  gan: Filbin, Megan E., et al.
  Cyhoeddwyd: (2012)
• Internal ribosomal entry site substitution eliminates neurovirulence in intergeneric poliovirus recombinants.
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  Cyhoeddwyd: (1996)