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The frequencies of calcium oscillations are optimized for efficient calcium-mediated activation of Ras and the ERK/MAPK cascade

Ras proteins are binary switches that, by cycling through inactive GDP- and active GTP-bound conformations, regulate multiple cellular signaling pathways, including those that control growth and differentiation. For some time, it has been known that receptor-mediated increases in the concentration o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kupzig, Sabine, Walker, Simon A., Cullen, Peter J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1103707/
https://ncbi.nlm.nih.gov/pubmed/15890781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409611102
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