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The frequencies of calcium oscillations are optimized for efficient calcium-mediated activation of Ras and the ERK/MAPK cascade

Ras proteins are binary switches that, by cycling through inactive GDP- and active GTP-bound conformations, regulate multiple cellular signaling pathways, including those that control growth and differentiation. For some time, it has been known that receptor-mediated increases in the concentration o...

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Detalhes bibliográficos
Main Authors: Kupzig, Sabine, Walker, Simon A., Cullen, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1103707/
https://ncbi.nlm.nih.gov/pubmed/15890781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409611102
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