Roles of the Human Immunodeficiency Virus Type 1 Nucleocapsid Protein in Annealing and Initiation versus Elongation in Reverse Transcription of Viral Negative-Strand Strong-Stop DNA

To study the initiation of human immunodeficiency virus type 1 reverse transcription, we have used the viral nucleocapsid protein (NC7) to anneal tRNA(3)(Lys) primer onto viral genomic RNA and have then eliminated NC7 from this primer-template complex by digestion with proteinase K and phenol-chloro...

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Detalhes bibliográficos
Main Authors: Rong, Liwei, Liang, Chen, Hsu, Mayla, Kleiman, Lawrence, Petitjean, Patrice, de Rocquigny, Hugues, Roques, Bernard P., Wainberg, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Animal Viruses
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC110360/
https://ncbi.nlm.nih.gov/pubmed/9765488
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