CD4(+) T-Lymphocyte Depletion in Human Lymphoid Tissue Ex Vivo Is Not Induced by Noninfectious Human Immunodeficiency Virus Type 1 Virions

We tested infectious human immunodeficiency virus type 1 (HIV-1), noninfectious but conformationally authentic inactivated whole HIV-1 virions, and purified gp120 for the ability to induce depletion of CD4(+) T cells in human lymphoid tissues ex vivo. Infectious CXCR4-tropic HIV-1, but not matched i...

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Pubblicato in:	J Virol
Autori principali:	Sylwester, A. W., Grivel, J.-C., Fitzgerald, W., Rossio, J. L., Lifson, J. D., Margolis, L. B.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Viral Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110358/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9765486/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.11.9345-9347.1998
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