Development of a Heterologous Model in Germfree Suckling Rats for Studies of Rotavirus Diarrhea

Germfree suckling rats were infected with an SA11 rotavirus strain. Infected pups developed diarrhea associated with histopathological changes. The virus was detected in feces and in the small intestine. Cellular vacuolation was observed in the villi of the jejunum. These results provide a new model...

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Hauptverfasser: Guerin-Danan, C., Meslin, J. C., Lambre, F., Charpilienne, A., Serezat, M., Bouley, C., Cohen, J., Andrieux, C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Viral Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC110350/
https://ncbi.nlm.nih.gov/pubmed/9765478
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