Subunit Rotavirus Vaccine Administered Parenterally to Rabbits Induces Active Protective Immunity

Virus-like particles (VLPs) are being evaluated as a candidate rotavirus vaccine. The immunogenicity and protective efficacy of different formulations of VLPs administered parenterally to rabbits were tested. Two doses of VLPs (2/6-, G3 2/6/7-, or P[2], G3 2/4/6/7-VLPs) or SA11 simian rotavirus in F...

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Autors principals: Ciarlet, Max, Crawford, Sue E., Barone, Christopher, Bertolotti-Ciarlet, Andrea, Ramig, Robert F., Estes, Mary K., Conner, Margaret E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
Matèries:
Viral Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC110343/
https://ncbi.nlm.nih.gov/pubmed/9765471
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