The PK Domain of the Large Subunit of Herpes Simplex Virus Type 2 Ribonucleotide Reductase (ICP10) Is Required for Immediate-Early Gene Expression and Virus Growth

The large subunit of herpes simplex virus (HSV) ribonucleotide reductase (RR), RR1, contains a unique amino-terminal domain which has serine/threonine protein kinase (PK) activity. To examine the role of the PK activity in virus replication, we studied an HSV type 2 (HSV-2) mutant with a deletion in...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Smith, C. C., Peng, T., Kulka, M., Aurelian, L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Animal Viruses
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110331/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9765459/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.11.9131-9141.1998
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