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The PK Domain of the Large Subunit of Herpes Simplex Virus Type 2 Ribonucleotide Reductase (ICP10) Is Required for Immediate-Early Gene Expression and Virus Growth

The large subunit of herpes simplex virus (HSV) ribonucleotide reductase (RR), RR1, contains a unique amino-terminal domain which has serine/threonine protein kinase (PK) activity. To examine the role of the PK activity in virus replication, we studied an HSV type 2 (HSV-2) mutant with a deletion in...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Virol
Principais autores: Smith, C. C., Peng, T., Kulka, M., Aurelian, L.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 1998
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110331/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9765459/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.11.9131-9141.1998
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