Oral Immunization of Macaques with Attenuated Vaccine Virus Induces Protection against Vaginally Transmitted AIDS

The chimeric simian-human immunodeficiency virus SHIV(KU-1), bearing the envelope of human immunodeficiency virus type 1 (HIV-1), causes fulminant infection with subtotal loss of CD4(+) T cells followed by development of AIDS in intravaginally inoculated macaques and thus provides a highly relevant...

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Bibliographic Details
Main Authors: Joag, Sanjay V., Liu, Zhen Qian, Stephens, Edward B., Smith, Marilyn S., Kumar, Anil, Li, Zhuang, Wang, Chunyang, Sheffer, Darlene, Jia, Fenglan, Foresman, Larry, Adany, Istvan, Lifson, Jeff, McClure, Harold M., Narayan, Opendra
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1998
Subjects:
Viral Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC110324/
https://ncbi.nlm.nih.gov/pubmed/9765452
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