An Adenovirus Type 5 Mutant with the Preterminal Protein Gene Deleted Efficiently Provides Helper Functions for the Production of Recombinant Adeno-Associated Virus

Production of recombinant adeno-associated virus (rAAV) requires helper functions that have routinely been provided by infection of the producer cells with adenovirus. Complete removal and/or inactivation of progeny adenovirus, present in such rAAV preparations, presents significant difficulty. Here...

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Pubblicato in:	J Virol
Autori principali:	Maxwell, Ian H., Maxwell, Francoise, Schaack, Jerome
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Gene Therapy
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110217/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9733887/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.10.8371-8373.1998
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