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Sequences Just Upstream of the Simian Immunodeficiency Virus Core Enhancer Allow Efficient Replication in the Absence of NF-κB and Sp1 Binding Elements

Large deletions of the upstream U3 sequences in the long terminal repeats (LTRs) of human immunodeficiency virus and simian immunodeficiency virus (SIV) accumulate in vivo in the absence of an intact nef gene. In the SIV U3 region, about 65 bp just upstream of the single NF-κB binding site always re...

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Udgivet i:J Virol
Principais autores: Pöhlmann, Stefan, Flöss, Stefan, Ilyinskii, Petr O., Stamminger, Thomas, Kirchhoff, Frank
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
Fag:
Animal Viruses
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110216/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9621017/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.7.5589-5598.1998
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