Naïve and Memory CD4 T Cells Differ in Their Susceptibilities to Human Immunodeficiency Virus Type 1 Infection following CD28 Costimulation: Implications for Transmission and Pathogenesis

In vitro evidence suggests that memory CD4(+) cells are preferentially infected by human immunodeficiency virus type 1 (HIV-1), yet studies of HIV-1-infected individuals have failed to detect preferential memory cell depletion. To explore this paradox, we stimulated CD45RA(+) CD4(+) (naïve) and CD45...

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Bibliografski detalji

Izdano u:	J Virol
Glavni autori:	Riley, James L., Levine, Bruce L., Craighead, Nancy, Francomano, Tara, Kim, Daniel, Carroll, Richard G., June, Carl H.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1998
Teme:	Viral Pathogenesis and Immunity
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110187/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9733871/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.10.8273-8280.1998
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