Naïve and Memory CD4 T Cells Differ in Their Susceptibilities to Human Immunodeficiency Virus Type 1 Infection following CD28 Costimulation: Implications for Transmission and Pathogenesis

In vitro evidence suggests that memory CD4(+) cells are preferentially infected by human immunodeficiency virus type 1 (HIV-1), yet studies of HIV-1-infected individuals have failed to detect preferential memory cell depletion. To explore this paradox, we stimulated CD45RA(+) CD4(+) (naïve) and CD45...

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Hlavní autoři: Riley, James L., Levine, Bruce L., Craighead, Nancy, Francomano, Tara, Kim, Daniel, Carroll, Richard G., June, Carl H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1998
Témata:
Viral Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC110187/
https://ncbi.nlm.nih.gov/pubmed/9733871
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