Nasal Immunization of Mice with Human Papillomavirus Type 16 Virus-Like Particles Elicits Neutralizing Antibodies in Mucosal Secretions

To specifically induce a mucosal antibody response to purified human papillomavirus type 16 (HPV16) virus-like particles (VLP), we immunized female BALB/c mice orally, intranasally, and/or parenterally and evaluated cholera toxin (CT) as a mucosal adjuvant. Anti-HPV16 VLP immunoglobulin G (IgG) and...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Balmelli, Carole, Roden, Richard, Potts, Alexandra, Schiller, John, De Grandi, Pierre, Nardelli-Haefliger, Denise
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Viral Pathogenesis and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110174/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9733865/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.10.8220-8229.1998
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