Deoxyribonucleoside Triphosphate Pool Imbalances In Vivo Are Associated with an Increased Retroviral Mutation Rate

Deoxyribonucleoside triphosphate (dNTP) pool imbalances are associated with an increase in the rate of misincorporation and hypermutation during in vitro reverse transcription reactions. However, the effects of in vivo dNTP pool imbalances on the accuracy of reverse transcription are unknown. We sou...

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Pubblicato in:	J Virol
Autori principali:	Julias, John G., Pathak, Vinay K.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Animal Viruses
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110126/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9733832/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.10.7941-7949.1998
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