Deoxyribonucleoside Triphosphate Pool Imbalances In Vivo Are Associated with an Increased Retroviral Mutation Rate

Deoxyribonucleoside triphosphate (dNTP) pool imbalances are associated with an increase in the rate of misincorporation and hypermutation during in vitro reverse transcription reactions. However, the effects of in vivo dNTP pool imbalances on the accuracy of reverse transcription are unknown. We sou...

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izdano v:	J Virol
Principais autores:	Julias, John G., Pathak, Vinay K.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1998
Teme:	Animal Viruses
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110126/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9733832/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.10.7941-7949.1998
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