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Genotypic Changes in Human Immunodeficiency Virus Type 1 Associated with Loss of Suppression of Plasma Viral RNA Levels in Subjects Treated with Ritonavir (Norvir) Monotherapy

Ten subjects received 600 to 1,200 mg of the human immunodeficiency virus type 1 (HIV-1) protease inhibitor ritonavir per day. Following 2 weeks of therapy, plasma HIV RNA levels decreased by a mean of 1.57 (range, 0.89 to 1.96) log units. With continued therapy, HIV RNA levels began to rise in eigh...

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Udgivet i:J Virol
Principais autores: Eastman, P. Scott, Mittler, John, Kelso, Reed, Gee, Chris, Boyer, Eric, Kolberg, Janice, Urdea, Mickey, Leonard, John M., Norbeck, Daniel W., Mo, Hongmei, Markowitz, Martin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
Fag:
Animal Viruses
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110088/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573287/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.6.5154-5164.1998
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