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Computer simulations of protein functions: Searching for the molecular origin of the replication fidelity of DNA polymerases

The use of computers to simulate the functions of complex biological macromolecules is essential to achieve a microscopic description of biological processes and to model and interpret experimental data. Here we apply theoretical computational approaches to investigate the fidelity of T7 DNA polymer...

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Detalhes bibliográficos
Main Authors: Florián, Jan, Goodman, Myron F., Warshel, Arieh
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1100748/
https://ncbi.nlm.nih.gov/pubmed/15863620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408173102
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