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Interfacial folding and membrane insertion of designed peptides studied by molecular dynamics simulations

The mechanism of interfacial folding and membrane insertion of designed peptides is explored by using an implicit membrane generalized Born model and replica-exchange molecular dynamics. Folding/insertion simulations initiated from fully extended peptide conformations in the aqueous phase, at least...

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Bibliografiske detaljer
Main Authors: Im, Wonpil, Brooks, Charles L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1100747/
https://ncbi.nlm.nih.gov/pubmed/15860587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408135102
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