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High-Efficiency Gene Transfer into Normal and Adenosine Deaminase-Deficient T Lymphocytes Is Mediated by Transduction on Recombinant Fibronectin Fragments

Primary human T lymphocytes are powerful targets for genetic modification, although the use of these targets in human gene therapy protocols has been hampered by low levels of transduction. We have shown previously that significant increases in the transduction of hematopoietic stem and progenitor c...

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Détails bibliographiques
Auteurs principaux: Pollok, Karen E., Hanenberg, Helmut, Noblitt, Timothy W., Schroeder, Wendy L., Kato, Ikunoshin, Emanuel, David, Williams, David A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC110042/
https://ncbi.nlm.nih.gov/pubmed/9573255
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