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High-Efficiency Gene Transfer into Normal and Adenosine Deaminase-Deficient T Lymphocytes Is Mediated by Transduction on Recombinant Fibronectin Fragments

Primary human T lymphocytes are powerful targets for genetic modification, although the use of these targets in human gene therapy protocols has been hampered by low levels of transduction. We have shown previously that significant increases in the transduction of hematopoietic stem and progenitor c...

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Publicat a:J Virol
Autors principals: Pollok, Karen E., Hanenberg, Helmut, Noblitt, Timothy W., Schroeder, Wendy L., Kato, Ikunoshin, Emanuel, David, Williams, David A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110042/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573255/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.6.4882-4892.1998
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